Sperm toxicity testing laboratory

Oswaldien E. Claassens, J. Bernhard Wehr, Keith L. The human sperm motility assay was used as a measure of quality control in the IVF laboratory. The effects of albumin supplementation and incubation time on the sensitivity of the human sperm motility assay were investigated. The assay was also compared with mouse embryo development.

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Sperm toxicity testing: UK best practice guideline from the Association of Biomedical Andrologists.

Human Sperm Survival Assays (HSSA) - Embryotech Laboratories Inc

In order to ensure the quality and integrity of diagnostic semen analysis results, materials used should be tested to ensure that they do not interfere with sperm function. As a toxicity test, complex sperm function testing may be considered controversial, since the fertilizing capacity of single sperm can never be assured. In preference, sperm motility offers a unique means of assessing the toxicity of reagents and materials before they are used in routine practice. Motility is the semen parameter most likely to be influenced by the external environment.
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To investigate to see if there is a problem with your fertility. This is often performed if you are in a heterosexual relationship and your partner is having trouble becoming pregnant. It is also necessary after a vasectomy operation to ensure that the sterilisation operation was successful and that you are no longer fertile. This test is called a post-vasectomy semen analysis PVSA.
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It is also the most common assay used in laboratories to screen laboratory consumables for toxicity. Now Specific motility parameters describing the movements of spermatozoa in a more detailed manner can be obtained. Furthermore, the classification into motile, progressive, slow and immotile spermatozoa can be based on well-defined velocity thresholds.
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